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Epithelial & Stromal Cultures of the Human Prostrate
Androgen Responsiveness & Control of Growth & Differentiation

By Karine Goossens
June 2002
Leuven University Press
ISBN: 90-5867-215-8[book cover]
154 pages, illustrated
$69.00 paper original

Introduction. Materials and methods. Both retionoids and androgens are required to maintain or promote functional differentiation in reaggregation cultures of human prostate epithelial cells. Effects and characterziation of paracrine factors produced by human prostate stromal cells in bioassays using rat sertoli cells, LNCAP tumor cells and cultured prostate epithelial cells. Regulation of insulin-like growth factor-binding protein-3 production in LNCAP cells and cultured human prostate epithelial and stromal cells by ligands acting via nuclear receptors. General conclusion and perspectives. Summary. References.

Acta Biomedica Lovaniensia, No. 255