Huntington's Disease: Early
Detection & Progression of
Cognitive Changes in Patients &
Asymptomatic Mutation Carriers

By Jurgen Lemiere
December 2004
Leuven University Press
ISBN: 9058674223
143 pages, Illustrated, 6 " x 9 "
$92.50 Paper Original

This is a Ph.D. dissertation. Huntington's Disease (HD) is a dominantly inherited late onset neurodegenerative disorder, initially affecting the basal ganglia and especially the head of the caudate nucleus.

Eventually, atrophy is more diffuse extending to the cerebral cortex and other brain nuclei. A triad of progressive motor, cognitive, and emotional symptoms characterizes adult onset HD.

Contents include: General Introduction and Aims of the Study, Cognitive Changes in Patients with HD and Asymptomatic Carriers of the HD Mutation, Recent Memory and Recognition Memory in Huntington's Disease, Habitual Learning in Huntington's and Parkinson's Disease, Effect of Oral Creatine Supplementation on Cognition in HD, General Summary and Perspectives.

Acta Biomedica Lovaniensia, No. 326

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