Metabolism & Biological
Activities of C(2)-Ceramide
Acta Biomedical Lovaniensia No. 377

By Helena van Overloop
December 2006
Leuven University Press
Distributed By Coronet Books
ISBN: 9789058675804
156 pages, Illustrated, 6 1/4 x 9 1/2"
$99.50 Paper Original

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I. General introduction

Sphingolipids
Ceramide
Ceramide-1-phosphate
Aims and objectives
References

II. N-acylmigration in ceramides

Abstract
Methods and results
References

III. Further characterization of mammalian ceramide kinase: substrate delivery and (stereo)specificity, tissue distribution, and subcellular localization studies

Abstract
Introduction
Materials and methods
Results and discussion
References

IV. On the presence of C2-ceramide in mammalian tissues, possible relationship to etherphospholipids and phosphorylation by ceramide kinase

Abstract
Introduction
Materials and methods
Results and discussion
references

V. Ceramide-1-phosphate quantitation: application to mouse tissues

Abstract
Introduction
Materials and methods
Results and discussion
References

VI. Ceramide-1-phosphate mediated biology

Abstract
Introduction
Materials and methods
Results and discussion
References

VII. General discussion

C2-ceramide: a naturally occurring ceramide-analogue?
Phosphorylation of C2-ceramide by ceramide kinase
Phosphorylation of C2-ceramide by other kinase?
Intracellular ceramide transport
Ceramide signaling: a role for C2-ceramide?
Ceramide-1-phosphate: a new bioactive phosphosphingolipid
Future perspectives
References

Summary
Samenvatting

Medical Science

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