Regulation & Clinical Relevance of Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) In Human Cancers


By Anchit Khanna
January 2012
Tampere University Press
Distributed by Coronet Books Inc.
ISBN: 9789514486623
185 pages
$87.50 Paper original


Current study is the first PhD thesis in the world on a newly identified cancer causing protein Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A).

This study identifies the mechanisms that drive the expression of this newly identified cancer causing protein,CIP2A, in human cancers. We identify new signaling pathways which involve some well established cancer causing genes like MYC.

In addition to the mechanisms , we also demonstrate the clinical relevance, in the form of prognostic role, of CIP2A in human cancers for the first time.

 

Acta Universitatis Tamperensis No. 1689



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